Natsume is the Gym Leader of Yamabuki City's Gym, known officially as the Yamabuki Gym. She hands out the Marsh Badge to Trainers who defeat her. She possesses psychic abilities and specializes in Psychic-type Pokémon.
As Natsume's psychic powers increased, she grew more obsessed with developing them. She also became less emotional, using her abilities for destructive purposes. This caused a deep psychological rift, and the emotions she tried to shut off developed into a separate personality: a young girl who manifested as a puppet around Natsume. Natsume's mind was then divided into the cold, callous woman with a thirst for power and the little girl who just wanted to have fun.
Prior to befriending Ghost, Natsume was a menacing and strong Gym Leader. She was shown to be able to telepathically command her Yungerer. However, her lighthearted nature was seen briefly at the end of "Ghost VS Esper!".